Patient details

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In this panel, one can narrow down the subset of selected patients based on criteria that characterize the patient as a whole, such as HPV status or whether they are smokers. To do so, put the toggle buttons in one of the following three states:

  • Only patients are selected where the respective characterisitc is *positive*. E.g. in the case of "smoking status" this would select all smokers.
  • This selection means that no filtering will be performed regarding the corresponding patient characteristic.
  • Selecting this will only include patients in the subset that do not have the respective characteristic or it is negative (e.g. not-smoking or HPV negative).

Note: Just below the buttons there are three numbers that give a preview of how many of the currently selected patients can be categorized according to the respective characteristic. Here, the middle number indicates for how many patients the characteristic is unknown.

Note: All filters in the Patient characteristics panel are combined via AND operations. This means, if one selects + for HPV status and - for neck dissection, the selection includes only patients who are HPV positive AND did not receive neck dissction.

Warning: Dont forget to hit compute after you have changed your selection criteria.

958
0
296
581
295
378
1041
0
213
868
0
386

Primary tumor

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Filter the dataset further by tumor-specific details, like the lateralization of a patient's primary tumor, its location and/or T-category.

Next to the selected subsites and T-categories, this panel also displays how many patients presented with a tumor in the respective subsite / T-category.

Note: Both the subsites and T-categories are selected or deselected by clicking on the respective button. If it appears white on dark blue, it is selected. If it appears dark blue on light blue, it is deselected. For example, selecting 'T1' and 'T2' and 'Tonsil' will select all patients that have primary tumors located in the tonsil AND are T1 OR T2-category, i.e. different criteria are combined via AND operations whereas T-categories are connected via OR operations.

45
431
778
209
373
672

Location & Subsite

Oropharynx:

175

376

135

Hypopharynx:

55

Larynx:

2

19

0

119

Oral cavity:

0

119

158

91

99

T-stage

5
310
431
219
289

Datasets

287
263
331
373
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Since we collect and visualize datasets from different institutions here, one can of course select which ones should be considered. To do so, simply click on the respective institution's logo. It is selected, if the logo is outlined and deselected if it is not.

Modalities

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Choose which of the available modalities to include in the visualization. Only patients are considered that have at least one of the selected diagnoses available. One may choose how to combine these - possibly conflicting - diagnoses:

  • logical OR: A lymph node level (LNL) is reported as metastatic or involved as soon as one of the selected diagnoses reports a positive finding. Anything else is reported as healthy.
  • logical AND: LNL's are reported as involved only when all diagnoses agree on positive findings. If that is not the case, meaning that none or not all agree on such a finding, it is reported (rather optimistically) as healthy.
  • maxLLH: This computes the most likely involvement based on all available diagnostic modalities and their respective sensitivities & specificities for a patient.
  • rank: Similar to the maxLLh method, this uses the sensitivities & specificities of the available diagnostic modalities, but instead of combining all diagnoses into one, it accepts the most trustworthy diagnose for a given patient.

The sensitivities & specificities used are listed below:

Modality Specificity Sensitivity
CT 76.0% 81.0%
MRI 63.0% 81.0%
PET 86.0% 79.0%
Fine Needle Aspiration 98.0% 80.0%
Diagnostic Consensus 86.0% 81.0%
Pathology 100.0% 100.0%
Planning CT 86.0% 81.0%

contralateral

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Here the most important information is visualized. For each side of the neck (ipsilateral being the same side as the tumor, contralateral the opposite) it displays a row for each LNL. From left to right, that row consists of...

  • its roman numeral label (e.g. IV)
  • a three-way toggle-button to select a subset of patients that show metastases in that LNL () or are reported healthy (). Selecting the middle button () means that no filtering is performed
  • and a horizontal stacked bar that displays the ratio of patients with reports of metastases in that LNL to patients that appear to have a healthy LNL. Numbers to the left and right of that bar plot indicate the absolute numbers and give a brief explanation when hovering over them with the mouse pointer.

Note: If for some patients the involvement in a LNL is unknown, these patients are represented by the middle bar. This may for example occur when selecting FNP is diagnostic modality, which is performed only in selected LNL.

LNL select involvement (metastatic, unknown, healthy)
I both
30 71 1153
a
4 3 1247
b
28 4 1222
II both
130 4 1120
a
74 640 540
b
38 640 576
III
55 4 1195
IV
23 6 1225
V both
20 6 1228
a
2 929 323
b
2 929 323
VII
6 967 281

ipsilateral

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Here the most important information is visualized. For each side of the neck (ipsilateral being the same side as the tumor, contralateral the opposite) it displays a row for each LNL. From left to right, that row consists of...

  • its roman numeral label (e.g. IV)
  • a three-way toggle-button to select a subset of patients that show metastases in that LNL () or are reported healthy (). Selecting the middle button () means that no filtering is performed
  • and a horizontal stacked bar that displays the ratio of patients with reports of metastases in that LNL to patients that appear to have a healthy LNL. Numbers to the left and right of that bar plot indicate the absolute numbers and give a brief explanation when hovering over them with the mouse pointer.

Note: If for some patients the involvement in a LNL is unknown, these patients are represented by the middle bar. This may for example occur when selecting FNP is diagnostic modality, which is performed only in selected LNL.

LNL select involvement (metastatic, unknown, healthy)
I both
144 58 1052
a
11 1243
b
131 1123
II both
698 1 555
a
335 638 281
b
160 637 457
III
316 1 937
IV
89 2 1163
V both
90 4 1160
a
9 927 318
b
5 927 322
VII
37 703 514
Help
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From left to right the three buttons here are

  • the help button in light blue, opening this very menu
  • an info button in light orange that shows how many patients are in the currently narrowed-down subset and that redirects to a list of patients in that subset when pressed
  • the compute button in bright orange, which sends a request with the current selections to the server for an update of the visualized statistics

Finally, on the left in this box one can toggle between displaying absolute numbers or percentages.